If we think about the last 50 years of history and the next 50 years, what challenges lie at the intersection of ethics, philosophy, psychology, and values that may affect the worth of what we own, the enjoyment we derive from living, and even our survival as a species? Certainly, global warming, weather and climate change, toxic pollution, and the extinction of species are a few of them. Over-population, income/wealth inequality, technological inequality, cyber-warfare and risk, global violence, human migration, and the risk of pandemics are some others. Are these things linked to each other? What do they have in common as a root cause? Is it time to re-think how we structure our economies, our governments, and how we live our lives….or will these challenges be addressed by the magic of markets? If not, how can they be addressed?